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Primary Antibodies
Anti-pVHL [ABT-PVHL]
Anti-pVHL [ABT-PVHL]

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: V0120
Reactivity:Human
Application:IHC
Modification:Unmodified/ Total
Source:Monoclonal Mouse
Storage and Stablility:-20°C/1 year

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Immunohistochemical
Sample Sized mAbs 5477
Pathology Grade Abs
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Anti-pVHL [ABT-PVHL]

Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Kidney using pVHL antibody.

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Product Details
Product Name
Anti-pVHL [ABT-PVHL]
Description
von Hippel-Lindau tumor suppressor(VHL) Homo sapiens Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome.The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
Catalog No
V0120
Reactivity
Human
Application
IHC
Modification
Unmodified/ Total
Source
Monoclonal Mouse
Storage and Stablility
-20°C/1 year
Application Dilution
1: 100-200
Other Name
G7 protein; pVHL; Von Hippel-Lindau disease tumor suppressor; von Hippel-Lindau syndrome gene
Gene Name
VHL
UniProtKB
P40337
Clone ID
ABT-PVHL
Isotype
Mouse IgG
Localization
Synthetic peptide
Postive Tissue Control
Immunogen affinity purified
Immunogen
Anti-pVHL [ABT-PVHL] detects endogenous levels of total pVHL protein.
Purification
0.5%Bovine Serum Albumin (BSA), 0.1%Kathon CG/ICP, 10x Tris-Buffered Saline (TBS), Type 3 MilliQ H2O and 50% glycerol.
Specificity
Formulation
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Catalog No: V0120

Anti-pVHL [ABT-PVHL]

Price/Quantity:
$Sample Size

Size:
20μl

Primary Antibodies

    • ELISA Kits

    • Research Areas

    Cell Adhesion Proteins Cell Cycle Proteins Channel Proteins Exosome GDP/GTP Binding Proteins Growth Factors and Hormones Homeodomain Proteins Immunohistochemical Kinases and Phosphatases Signaling

     

    Membrane Receptors Neurobiology Signaling Intermediates Steroid Receptors Structural Proteins Synthesis and Degradation Transcription Regulators Transport and Trafficking Tumor Suppressors/Apoptosis
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